NMN Back on Top as FDA Confirms Its Legal Use in Dietary Supplements
After nearly three years of sustained advocacy by the Natural Products Association (NPA), the U.S. Food and Drug Administration (FDA) has reversed its position, formally recognizing β-nicotinamide mononucleotide (NMN) as a legal ingredient for dietary supplements.
NMN has become one of the most talked-about anti-aging compounds in recent years. Once ingested, it is rapidly utilized by the body:
within 15 minutes it is absorbed from the gut into the bloodstream, and within 30 minutes it boosts NAD⁺ synthesis in vital tissues such as the liver and skeletal muscle.
Chronic supplementation can sustain NAD⁺ levels in metabolically active organs like the liver and brown adipose tissue, laying the groundwork for delaying age-related functional decline.
Manufacturing technology for NMN continues to improve; enzyme-catalyzed processes now achieve high conversion rates, and future advances are expected to make the ingredient even more accessible as a supplement.
Food and Drug Administration (FDA) has reversed its position, formally recognizing β-nicotinamide mononucleotide (NMN) as a legal ingredient for dietary supplements.
