What is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide) is a key coenzyme in cells and is widely involved in energy metabolism, REDOX reactions and various signaling pathways. glutathione
The following is a summary of its basic information: The oxidizing type (NAD+) can accept electrons and participate in oxidation reactions.
The reduced form (NADH) carries electrons and participates in reduction reactions.
The main function is REDOX reactions – as an electron carrier, it transfers electrons in glycolysis, the tricarboxylic acid cycle (TCA cycle), and the mitochondrial electron transport chain, promoting ATP synthesis.
Non-oxidative function: Enzyme substrate: Provides ADP-ribose groups for various enzymes (such as PARPs, sirtuins, CD38), and participates in DNA repair, epigenetic regulation, and cellular stress response. Regulate physiological processes such as metabolism, aging, and circadian rhythms.
With age, NAD+ levels decrease and are associated with mitochondrial dysfunction, metabolic disorders, and aging-related diseases (such as neurodegenerative diseases and cardiovascular diseases).
Basic information of glutathione
Glutathione is actually a substance that our human body contains by itself. Just like the artificially synthesized tranexamic acid, it belongs to the category of amino acids.
In the medical field, GSH has a wide range of uses.
It can be used to treat liver diseases. For instance, in some hepatitis patients, the use of glutathione can help repair damaged liver cells and improve liver function.
In the field of ophthalmology, it also has a certain effect on the treatment of cataracts. Through its antioxidant effect, it delays the process of lens opacity.
Glutathione can also act as an antidote to help the human body eliminate some harmful substances.
The realization of these functions is all attributed to the powerful antioxidant effect of GSH.
It can neutralize the free radicals produced in the body, reduce the damage of free radicals to cells, and thereby maintain the normal functions of cells.
It is worth mentioning that glutathione is also a common food additive. In food processing, it mainly utilizes its own antioxidant and reductive properties.
For instance, adding GSH to some foods that are prone to oxidation and deterioration can extend the shelf life of the food, maintain its color and taste.
Proportioning scheme
When compounding with NAD+, first understand the specifications of GSH. The common specification of glutathione is that there are 10 bottles in one box, and the content of each bottle is 0.6g.
So, how exactly should it be proportioned?
The common practice is to first take 3-4 ml of normal saline and mix it evenly with 1.2g of glutathione.
Physiological saline is used here because its concentration is similar to that of extracellular fluid in human cells, which will not cause damage to cells and can also dissolve GSH.
After mixing well, dissolve 7 to 10 bottles of NAD+ and inject them together into 150ml of normal saline for intravenous drip for about 1 hour.
It should be noted that this dosage is not fixed.
Everyone has a different constitution, and their responses to body sensations also vary.
If your skin tone is darker or you find the effect not obvious enough after the first use, you can appropriately increase the dosage of NAD+.
However, when increasing the dosage, it should be done gradually and not too much at once to avoid adverse effects on the skin.
Usage suggestions
Some friends may find the effect not very satisfactory after using the compound formula.
What should be done in such a situation?
You can try increasing the dosage of NAD+. Follow the method mentioned earlier and gradually increase the dosage to see if it can improve the effect.
If the expected effect is still not achieved after increasing the dosage, it can be considered to switch to tranexamic acid.
Tranexamic acid is also a component often used in the compounding of water light injections, and it has a good effect on whitening and fading spots.
