Enforce quality standards：ISO09001
Extraction source：Enzymatic catalysis
Packaging：Inner ziplock bag, outer aluminum foil bag
Main ingredients：Enzyme catalysis
Usage：Used in health care products
NMN (full name: β-Nicotinamide Mononucleotide) - "C11H15N2O8P", a molecule that exists naturally in all forms of life. At the molecular level, it is ribonucleic acid, the basic structural unit of the nucleic acid RNA. Structurally, the molecule is composed of nicotinamide groups, ribose and phosphate groups. NMN is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and is considered a key component in increasing intracellular NAD+ levels.
So what are the sources of raw materials for NMN?
Although many plants contain natural NMN, such as broccoli, avocado, etc., the content is very small and it is difficult to obtain it directly from plants. According to research by Professor Imai of the University of Washington , to obtain the daily requirement of NMN from broccoli, taking 250 mg as an example, 100 kilograms of broccoli, 69 kilograms of avocado, or 416 kilograms of beef are required. In fact, it is unrealistic to obtain natural NMN from animals and plants, considering the losses during the extraction process.
The first generation of commercialized NMN came from Japan and was produced through microbial fermentation. Due to the low yield of microbial fermentation, which is not conducive to industrialization and the cost remains high, it was later replaced by enzymatic synthesis.
In proportion to the fermentation method, the yield of NMN synthesized by enzymatic method has been greatly improved, which has promoted the large-scale production of NMN and is the second generation of commercialized NMN. The yield and purity of the enzyme synthesis method are directly related to the activity and purity of the enzyme. Once the enzyme is inactivated or contaminated, the product will be affected.
Chemical synthesis is the third generation of commercialized NMN that has recently emerged, which can enable large-scale industrial production, increase output, and reduce costs. At the same time, chemical synthesis achieves stable quality and high repeatability between tolerances through precise control of reaction conditions.
Whether it is biosynthetic or chemical synthesis, natural or non-natural, through modern detection methods, we will find that the molecular structure of NMN is the same. The safety and effectiveness of raw materials must be ensured through final testing, including purity, content, microorganisms, heavy metals, etc.
NMN itself is a naturally occurring substance in humans and organisms. Judging from the fact that breast milk contains NMN, it can be said to be one of the first nutrients humans consume after birth. Yellow and green vegetables also contain NMN, so unlike drugs, NMN is a naturally derived food and is safe. However, the possibility of individual effects such as food allergies cannot be ruled out.
David Sinclair, professor of genetics at Harvard, proposed that W+NMN12000 has the effect of reversing aging: by maintaining sufficient NAD+ in cells, it can maintain the self-repair ability of DNA and effectively repair DNA damage caused by age. repair, thereby inhibiting aging. NMN raw material is the precursor of NAD+, and taking W+NMN12000 can increase the level of NAD+ in the body.