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Get to Know γ-Glutamylcysteine

by: GSHWORLD Time: 2025-10-13 Classify: Product News

γ-Glutamylcysteine (γ-GC) is a dipeptide formed by the condensation of glutamic acid and cysteine. Inside the cell it combines with glycine under the catalysis of glutathione synthetase (GSS) to produce glutathione (GSH), making γ-GC the immediate precursor of GSH. By being converted to GSH, γ-glutamylcysteine helps scavenge oxygen free radicals, detoxify reactive oxygen species, modulate enzyme activity, take part in metabolism, and strengthen immunity.


Get to Know γ-Glutamylcysteine

Areas of Application

Medicine

GSH synthesis: γ-GC is the key precursor for glutathione, one of the body's master antioxidants. Pharmaceutical-grade GSH is used as an antioxidant, detoxifier, and anti-fatigue agent.

Drug development: Owing to its central role in antioxidant defense, γ-GC is being explored for new drugs aimed at preventing or treating oxidative-stress-related disorders.

Food Industry

Antioxidant: γ-GC and its derivatives retard lipid oxidation, inhibit browning, prolong shelf life, and enhance flavor in processed foods.

Functional foods: The dipeptide serves as a bioactive ingredient in health foods and oral supplements.

Biochemical Research

Laboratory reagent: γ-GC is routinely employed as a reductant/antioxidant to protect proteins and enzymes and to preserve cell integrity.

Research tool: It is used to probe the active sites and kinetics of glutathione synthetase.

Agriculture

Plant protection: In plants, γ-GC is converted to phytochelatins that chelate heavy metals and mitigate metal-induced oxidative stress.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

 

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