Nicotinamide riboside (NR) is essentially a form of vitamin B3, but is structurally and biochemically different from niacin (NA) and nicotinamide (NAM), which are alternatives to other vitamin B3s.
Vitamin B3 is an essential micronutrient required to maintain NAD+ (nicotinamide adenine dinucleotide) levels. Vitamin B3 called nicotinamide riboside was discovered in yeast in the 1940s. But it wasn’t until the early 2000s that scientists began to see the potential of this vitamin B3 to not only increase NAD+ but also improve human health. In 2004, a Dartmouth College research team discovered that nicotinamide riboside, like its vitamin B3 brother, is a precursor to NAD+.
Even before we see the effects of aging, metabolic changes occur beneath the skin. Choosing to approach our health from the inside out may be just what we need to improve the way we age.
Nicotinamide riboside can also activate cell repair-promoting proteins sirtuins. As we age, these sirtuins work overtime to help cells stay strong.
Staying healthy as you age is never going to be as simple as one vitamin, even with one as promising as nicotinamide riboside. There are over 100 studies investigating nicotinamide riboside, many of which have linked increased NAD+ levels to metabolic and muscle health in mice. Additional research is ongoing to understand the role of NAD+ in supporting other age-related health challenges, including decreased liver function, weight gain, insulin levels and brain function in mice.
*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.