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The great physiological effects of glutathione

Author: GSHWORLD Release time: 2023-10-18 Column: Product News


Glutathione is a tripeptide composed of glutamic acid, cysteine and glycine, including reduced glutathione (GSH), oxidized glutathione (GSSG), acetyl glutathione (SAG ).


Glutathione may delay nucleus pulposus cell apoptosis and matrix destruction, thereby preventing and treating intervertebral disc degeneration.

The number and function of mesenchymal stem cells in patients with steroid-induced femoral head necrosis are reduced, the level of intracellular reactive oxygen species is increased, the osteogenic capacity is reduced, and the adipogenic capacity is enhanced. Glutathione can reverse this by reducing the level of intracellular reactive oxygen species. Variety.

Glutathione can directly or indirectly scavenge free radicals by participating in redox reactions catalyzed by superoxide dismutase (SOD), glutathione peroxidase (GPx) and other enzymes, accelerating the proliferation and differentiation of osteoblasts. , promote the repair of new bone in the tibial bone defect.

Animal experiments have found that oral supplementation of glutathione will significantly reduce plasma non-esterified fatty acids, increase intramuscular pH, and significantly increase peroxisome proliferator-activated receptor γ-coactivator-1α protein and mitochondrial DNA levels. It can inhibit the increase of lactic acid in muscles, thereby improving metabolism and relieving muscle fatigue caused by long-term activities.

Nervous system diseases are diseases that occur in the central nervous system, peripheral nervous system, and autonomic nervous system and are mainly characterized by sensory, motor, consciousness, and autonomic nerve dysfunction.

Glutathione can reduce NO-mediated hyperphosphorylation of retinal lipids and proteins, inhibit NO down-regulation of paraoxonase-2, β-actin, and β-tubulin, suggesting that glutathione may be useful in glaucoma. prevention and control.

A large number of studies have shown that glutathione is an important coenzyme factor that acts as a neuromodulator in the nervous system and can inhibit oxidative stress-mediated damage.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.


Tag: Glutathione GSH

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