How do Citicoline supplements improve memory and attention?

 

Citicoline is an endogenous compound that participates in the synthesis of cell membrane phospholipids. Reviewing a large number of experimental studies and clinical trials, it can not only improve neurological function, but also promote nerve regeneration and repair.

Effects of Citicoline on Memory

Protecting nerve cell membranes: Promoting phospholipid synthesis and repairing damaged nerve cell membranes. In cases of brain injury and ischemia, it can reduce cell membrane damage and free fatty acid release. For example, in experimental cerebral ischemia models, it can inhibit phospholipase A₂ activity and reduce nerve cell damage.

Improving brain metabolism: Improving brain energy metabolism, increasing glucose uptake and utilization, and improving energy crisis after cerebral ischemia. For example, in animal experiments, it can restore mitochondrial ATPase activity and improve brain energy metabolism.

Regulating neurotransmitters: Increasing the levels of neurotransmitters such as dopamine and acetylcholine, improving cognitive and motor functions. For example, in Parkinson's disease models, it can enhance dopaminergic transmission and relieve movement disorders.

Anti-inflammatory and antioxidant: Reduce free radical generation, inhibit inflammatory response, reduce oxidative stress and neuroinflammation after brain injury, such as in traumatic brain injury models, it can reduce inflammatory factor levels and reduce neuronal apoptosis.

As a precursor for phospholipid synthesis, citicoline can increase acetylcholine levels in the brain, thereby improving cognitive function.

In clinical trials, citicoline has been shown to improve attention and may have a positive effect on memory loss caused by aging.

Currently, there is sufficient evidence that citicoline can improve neurological function and quality of life. Future research may focus on optimizing dosage, combining with other ingredients, and expanding new indications.

References:

[1] Kansakar U, Trimarco V, Mone P, et al. Choline supplements: An update[J]. Frontiers in endocrinology, 2023, 14: 1148166.

[2] Secades J J, Gareri P. Citicoline: pharmacological and clinical review, 2022 update[J]. Rev Neurol, 2022, 75(s05): S1-S89.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

by GSHWORLD

GSHWORLD is China Biological API Manufacturer. China Citicoline Supplements powder suppliers & best Citicoline benefits raw material Factory.