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NMN and mycoplasma pneumonia

Author: GSHWORLD Release time: 2023-12-12 Column: Product News


Mycoplasma is a microorganism that is on a tiny scale between bacteria and viruses and widely exists in nature, and Mycoplasma pneumoniae is one of them. After Mycoplasma pneumoniae infects the human body, it causes a series of pathological changes, mainly manifested as an inflammatory reaction in the interstitial tissue of the lungs, which is called mycoplasma pneumonia.

The inflammatory response, lung tissue damage, and increased mucus secretion caused by mycoplasma infection will have a negative impact on lung function and structure. Therefore, it is particularly important to seek effective treatments to protect lung health.

Recent studies have shown that NMN, as a potential substance with anti-aging and anti-inflammatory effects, has a positive impact on the maintenance of lung health. 


Several research papers have affirmed the role of NMN in promoting lung organ health.

1. NMN can improve the aging of alveolar epithelial cells

2. NMN improves MT in acute lung injury by inducing mitotic nucleoprotein imbalance and activating UPR

3. NMN improves silica-induced lung injury in mice through the Nrf2-regulated glutathione metabolism pathway

4. High-dose NMN promotes ferroptosis to inhibit the growth of lung adenocarcinoma through the NAM-mediated SIRT1-AMPK-ACC pathway.

5. NMN can reduce LPS-induced acute lung injury and has anti-inflammatory, antioxidant and anti-apoptotic effects

6. Evaluate the effects of NMN supplementation on lung inflammation in male mice sub-chronically exposed to environmental particulate matter

Research shows that NMN has anti-inflammatory effects and can reduce inflammatory responses and symptoms of inflammation-related diseases.

Secondly, NMN supplementation can improve mitochondrial function and energy metabolism, thereby helping to support the normal function and repair processes of lung cells.

NMN is a health product and dietary supplement that does not have the effect of directly treating mycoplasma pneumonia and cannot have a specific therapeutic effect on the disease itself.

Nonetheless, NMN's adjuvant effects can boost immunity and improve lung health, helping the body better cope with and recover from mycoplasma pneumonia infection.


[1]Fang T, Yang J, Liu L, Xiao H, Wei X. Nicotinamide Mononucleotide ameliorates senescence in alveolar epithelial cells. MedComm (2020). 2021 May 27;2(2):279-287. doi: 10.1002/mco2.62. PMID: 34766147; PMCID: PMC8491199.

[2]Du SH, Shi J, Yu TY, Hu XX, He SM, Cao YY, Xie ZL, Liu SS, Li YT, Li N, Yu JB. Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPRmt. Exp Biol Med (Maywood). 2022 Jul;247(14):1264-1276. doi: 10.1177/15353702221094235. Epub 2022 May 10. PMID: 35538652; PMCID: PMC9379602.

[3]Wang L, Zhao M, Qian R, Wang M, Bao Q, Chen X, Du W, Zhang L, Ye T, Xie Y, Zhang B, Peng L, Yao Y. Nicotinamide Mononucleotide Ameliorates Silica-Induced Lung Injury through the Nrf2-Regulated Glutathione Metabolism Pathway in Mice. Nutrients. 2022 Dec 28;15(1):143. doi: 10.3390/nu15010143. PMID: 36615800; PMCID: PMC9823503.

[4]Zhang M, Cui J, Chen H, Wang Y, Kuai X, Sun S, Tang Q, Zong F, Chen Q, Wu J, Wu S. High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1-AMPK-ACC Pathway. Cancers (Basel). 2023 Apr 23;15(9):2427. doi: 10.3390/cancers15092427. PMID: 37173894; PMCID: PMC10177531.

[5]Tian Y, Zhu CL, Li P, Li HR, Liu Q, Deng XM, Wang JF. Nicotinamide Mononucleotide Attenuates LPS-Induced Acute Lung Injury With Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects. J Surg Res. 2023 Mar;283:9-18. doi: 10.1016/j.jss.2022.09.030. Epub 2022 Nov 5. PMID: 36347171.

[5]Zhang R, Chen S, Wang Z, Ye L, Jiang Y, Li M, Jiang X, Peng H, Guo Z, Chen L, Zhang R, Niu Y, Aschner M, Li D, Chen W. Assessing the Effects of Nicotinamide Mononucleotide Supplementation on Pulmonary Inflammation in Male Mice Subchronically Exposed to Ambient Particulate Matter. Environ Health Perspect. 2023 Jul;131(7):77006. doi: 10.1289/EHP12259. Epub 2023 Jul 17. PMID: 37458712; PMCID: PMC10351503.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.


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