The mechanism and characteristics of citicoline

 

Citicoline is an activator of energy metabolism of central nervous cells, which can effectively promote the metabolism of brain cells and improve brain function. It is often used clinically to treat central system diseases such as cerebral infarction, brain atrophy, and senile dementia. Clinical studies have shown that it Can effectively protect brain cells and promote nervous system recovery.

First of all, citicoline can effectively improve the microcirculation of the brain and promote blood supply to the brain. Patients with cerebral infarction often have insufficient blood supply to local tissues, leading to stress reactions in brain blood vessels, vasoconstriction, and blood viscosity will gradually increase, which will further aggravate brain deficiency and hypoxia. Pharmacological studies have shown that citicoline can effectively dilate blood vessels in the brain. Reduce cerebrovascular resistance, while citicoline can reduce blood viscosity, thereby effectively improving cerebral circulation, reducing the size of cerebral infarction, and protecting the integrity of brain structure.

Second, citicoline can improve energy metabolism in brain cells. When cerebral infarction occurs, brain cells will have abnormal energy metabolism due to hypoxia deficiency, resulting in a decrease in the synthesis of endogenous citicoline, which in turn will lead to brain cells being unable to resist hypoxia deficiency and apoptosis. Citicoline can effectively increase the level of citicoline in brain cells, promote the energy metabolism of cells, improve the tolerance of brain cells against hypoxia, maintain the integrity of brain cells, and maintain the normal function of the brain.

Third, citicoline can repair damaged brain cells. Citicoline can effectively increase the permeability of brain cells to sodium ions, increase the uptake of glutamate by glial cells, and can promote and repair damaged nerve cells.

Finally, citicoline can increase brain excitability and enhance the function of the pyramidal system. Pharmacological studies have shown that citicoline can mediate the rapid excitation of the central nervous system, thereby enhancing the function of the brainstem reticular structure ascending activation system, and at the same time, it has the effect of enhancing the pyramidal system, improving limb paralysis, and has the effect on the brain controlling limb movement. A certain boost.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.