Citicoline Sodium is an intermediate in the process of synthesizing phosphatidylcholine, which mainly plays an important role in the formation of biofilm. At the same time, it also plays a very obvious role in the conduction of bioelectricity and the transfer of nerve media.
Citicoline sodium is a derivative of nucleic acid, the main coenzyme for the biosynthesis of lecithin, and an activator of body metabolism. The pharmacological mechanism of citicoline sodium has been confirmed by research: after citicoline enters the patient's body. It can pass through the blood-brain barrier and combine with the membrane phospholipids in the brain cells of patients to promote the synthesis of membrane phospholipids and the metabolism of the brain. At the same time, it can also increase the activity of mitochondrial ATPase and membrane Na+/K-ATPase. The activity of enzyme A is inhibited, which plays a role in stabilizing the brain cell membrane and protecting the patient's brain cells.
Citicoline sodium has a protective effect on neurons and can improve the cognitive function of patients. When citicoline sodium is hydrolyzed, it can provide choline, and choline can promote Ach secretion and neuromembrane phospholipid synthesis. Ach can excite choline It can protect the functional integrity of the central nervous system and finally relieve symptoms such as memory loss and cognitive impairment.
Citicoline sodium can reduce cerebrovascular resistance, increase cerebral blood flow, thereby improving microcirculation and promoting brain substance metabolism. In addition, citicoline sodium can also enhance the function of the ascending activation system of the brainstem reticular structure, thereby enhancing the function of the pyramidal system, improving motor paralysis, promoting brain awakening and functional recovery, and has a good effect in the treatment of senile dementia patients. Cognitive dysfunction in patients will affect their daily life, and citicoline sodium can quickly improve the cognitive function of patients, so the ability of daily life has also been improved.
Studies have proved that citicoline sodium can also effectively reduce the cerebral edema of patients, protect the brain nerve function of patients, inhibit the delayed death of brain neurons, prevent the damage of vascular endothelial cells, and play an anti-ischemic role.