Glutathione Has Important Effects On Skin And Various Cells in Skin
Telorack et al found that low concentrations of Glutathione were sufficient to support the growth of keratinocytes and wound healing in mouse experiments.
In mice deficient in vitamin A (vitamin A is also an important antioxidant), Glutathione played an important role as an antioxidant.
The higher the level of Glutathione in the mouse skin, the lower the level of ROS (reactive oxygen species free radicals).
Antioxidant and whitening are related.
In an open-label trial in the Philippines, women with type VI and type V took lozenges containing Glutathione for 8 weeks, and after two weeks, they saw a reduction in melanin and no adverse effects.
In a double-blind, randomized controlled trial in Thailand, subjects were given Reduced Glutathione (250 mg/d) or Oxidized Glutathione (250 mg/d) or placebo for 12 consecutive weeks to test skin melanin index, wrinkles and other physiological indicators, It was found that both the GSH group and the GSSG group tended to reduce melanin and wrinkle improvement, while the Glutathione group had a more significant wrinkle improvement effect.
Skin elasticity also improved in both test groups. No serious adverse reactions were found in the study.
(A friendly reminder here: One of the main ingredients in many whitening pills is Glutathione.)
There is a very interesting study done by Chung B Y et al. They used in vitro cell experiments and found that extracellular Glutathione itself does not inhibit melanin synthesis, but extracellular Glutathione monoethyl ester can significantly inhibit melanin synthesis.
Therefore, Glutathione may be converted into monoethyl ester in the body and then play a role, or play a role directly, or play a whitening effect through other ways, it is necessary to further confirm, because other studies have found that Glutathione can inhibit the synthesis of melanoma cells Melanin, the results of this study also need to be repeated.
In any case, the free radical scavenging effect of Glutathione and the inhibition of melanin synthesis by intracellular GSH are conclusive.
*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.
by GSHWORLD
GSH Bio Tech is China Biological API Manufacturer. China Glutathione powder suppliers & best Glutathione raw material Factory.
