The essence of NMN is to increase the concentration of NAD+ by supplementing NAD+ precursor substances, maintain the transmission of information between mitochondria and the nucleus, and exert the function of mitochondria to provide energy for cells.
More and more research institutions have proved that NMN participates in various physiological activities such as cell material metabolism, energy synthesis, and cell DNA repair in the body, and can obviously produce effects of resisting diseases, consolidating health, and delaying the aging process of the human body.
In March this year, the authoritative journal "Nature Communication" published a study proving that NMN supplementation can effectively prevent myelin aging and promote the repair of myelin after injury. "Genes & Diseases" also systematically discussed the beneficial effects of NAD+ on cardiovascular diseases. It has broad application prospects in coronary heart disease, arrhythmia and heart failure.
NMN is also effective in improving Alzheimer's disease. Genetics, environment and aging are the three major influencing factors leading to the onset of Alzheimer's disease. At present, there is no drug that can cure Alzheimer's disease, and clinical diagnostic techniques and methods are long-term problems. Early identification and early intervention are the most effective ways to delay Alzheimer's disease.
The study found that NMN significantly reduced beta-amyloid production, brain amyloid plaque burden, loss of brain synapses, and inflammatory responses in transgenic animals.
▲NMN significantly reduced the plaques formed by β-amyloid in brain tissue
Another study from Chinese scientists found that intravenous injection of NMN in experimental mice can increase the level of NAD+ in the brain, and NMN reduced cerebral infarction within 24 hours after middle cerebral artery occlusion (MCAO). The effect of NMN on acute ischemic stroke injury was shown, and the safety was confirmed again.
In terms of clinical research, the Norwegian Haukeland University Hospital and the Department of Clinical Medicine of the University of Bergen published research results on Cell Metabolism: the intake of NAD+ precursors can increase the level of NAD+ in the brains of patients with Parkinson's disease, thereby protecting the nervous system and improving Parkinson's disease effect of the disease.
It has been demonstrated that NMN can help restore cognition in rats with Alzheimer's disease, and the beneficial effects of NMN are produced by improving nerve cell survival, improving energy metabolism and reducing the accumulation of reactive oxygen species (ROS) in the hippocampus of brain tissue, These results suggest that NMN is promising to cooperate with the improvement of Alzheimer's disease.
*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.