Nicotinamide riboside (NR) is a form of vitamin B3 that serves as a precursor to NAD+, a coenzyme that plays a key role in many body processes.
Our NAD+ levels naturally decline as we age, and low levels of the coenzyme are associated with aging and some common health conditions, such as heart disease and neurodegenerative diseases.
Nicotinamide riboside has gained attention for its ability to increase NAD+ levels.
Possible potential benefits
1. Stimulate NAD+ metabolism
A recent study conducted at the University of Colorado found that nicotinamide riboside supplementation effectively stimulated NAD+ metabolism in healthy middle-aged and older adults.
The researchers found that not only was NR supplementation well tolerated by participants, but it may also be beneficial in lowering blood pressure and arterial stiffness.
NAD+ deficiency is a common core cause of aging and many diseases, and research shows that restoring NAD+ levels has tremendous therapeutic and nutritional value.
2. Improve sports performance
A 2019 study published in the European Journal of Nutrition found that using nicotinamide riboside supplements improved physical function and reduced oxidative stress in older adults.
Researchers believe that NR supplementation may benefit NAD+ deficient individuals.
A study published in Scientific Reports evaluated the safety and metabolism of NR supplements.
Researchers found that when NR was given at doses of 100, 300 and 1,000 mg in an 8-week randomized, double-blind, placebo-controlled clinical trial, it effectively increased NAD+ levels without causing any adverse events.
This article is for informational purposes only and does not provide any medical advice. If you need to take supplements, please be sure to consult your healthcare professional.
*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.