Product Characteristics of Citicoline Sodium

 

Citicoline Sodium is a common neuroprotective agent, which can repair and protect nerve cells and improve energy metabolism in the brain. It is widely used clinically in neurology, ophthalmology, rehabilitation, geriatrics, ENT and other departments.

Pharmacological action of citicoline sodium

1. Protect cell membrane lipid structure

◆ Synthesize phospholipid (lecithin), repair neuron cell membrane and mitochondrial membrane

◆ Inhibit phospholipid decomposition (phospholipase A1, A2 activity ↓)

◆ Reduce the release of free fatty acids and lipid peroxidation

◆Blocking the toxicity of excitatory amino acids

2. Maintain the energy metabolism of the brain

◆ Emulsify and decompose fat, reduce blood viscosity and lower blood cholesterol

◆ Improve cerebrovascular tension and increase cerebral blood flow

◆ Increase the uptake of glucose and oxygen

◆ Restore the activity of ATPase (mitochondrial ATPase, Na/K-ATPase)

3. Exciting neurotransmitter action

◆ Increase the synthesis of acetylcholine

◆ Increase the synthesis of dopamine

4. Other effects on brain tissue

◆ Promote the reabsorption of cerebral edema

◆ Synthesize glutathione to maintain antioxidant effect

◆ Inhibit cell apoptosis

5. Clinical application

Sequelae of traumatic brain injury; ischemic encephalopathy; facial neuritis; intractable vertigo; diabetic peripheral neuropathy; glaucoma, amblyopia, optic atrophy.