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Related effects of glutathione in skin

Author: GSHWORLD Release time: 2023-11-24 Column: Product News


Glutathione is a tripeptide compound contained in all living cells. It is a combination of glutamic acid, cystine and glycine. It is an important intermediate substance in biological metabolism.

Glutathione has two configurations: reduced and oxidized. The reduced form can reduce the oxidized -S-S-bond in biological enzymes to -SH group, thereby restoring or improving their activity.

Related effects of glutathione in skin

Glutathione related experimental data:

1. Whitening

Glutathione has reducing ability. During the formation of melanin, reduced glutathione can reduce the oxidized dopaquinone and convert it into glutathione dopa to generate lighter-colored pheomelanin. It can inhibit tyrosinase activity and has whitening effect.

Experimental data show that 1 mg/ml reduced glutathione can inhibit tyrosinase activity by 92.5%, while 100 mg/ml oxidized glutathione can only inhibit tyrosinase activity by 88.3%. %.

2. Antioxidant

Judging from the in vitro experimental results of scavenging DPPH free radicals, HO·free radicals, and superoxide anion free radicals, the activity and efficacy of reduced glutathione (GSH) are more prominent.

3. Anti-allergy

The anti-allergic activity of glutathione in vitro and in vivo was studied, and a hyaluronidase inhibition rate experiment was used to study the anti-allergic effect of glutathione in vitro.

When the concentration of glutathione reaches 5 mg/mL, the inhibition rate of hyaluronidase can reach 70.83%. Its inhibitory effect is similar to the anti-allergic effect of 50 μg/ml chlorpheniramine, and it has strong anti-allergic activity.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

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