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The effect of glutathione on melanin

Author: GSHWORLD Release time: 2023-08-15 Column: Product News


The main reason for darkening is the production of melanin in the skin. Skin "blackening" is a complete and complex link produced by melanin, transported, and then released to the surface of the skin.

What is Tyrosinase?

Tyrosinase is an important biological enzyme with dual catalytic functions in the human body. It participates in the regulation of melanin synthesis in the human body and plays a key role in the formation of melanin in the human body. When the melanin metabolism process or epidermal melanin deposition is disordered, that is Pigmentation disorders can occur, divided into hypopigmentation and hyperpigmentation. In the production of melanin, tyrosinase undoubtedly plays a key role.

melanin formation

Human melanin is synthesized in melanocytes. The formation of melanin requires two basic substances: the first is tyrosine, which is a substrate for the reaction; the second is tyrosinase, which is the substrate for the reaction. A catalyst that can convert tyrosine into melanin. A large number of medical research and clinical experiments have confirmed that tyrosinase is the key enzyme for melanin synthesis. Without the participation of tyrosinase, tyrosine cannot be converted into melanin. .

Effects of Tyrosinase on the Skin

Increased tyrosinase activity will catalyze the conversion of tyrosinase to melanin in a large amount. A large amount of melanin will appear in a short period of time. If the human body does not metabolize it in time, it will cause pigmentation, such as nevus of Ota, freckles, chloasma, age spots, dark spots, etc. Moles and other skin problems are closely related to human aging. The activity of tyrosinase is reduced, the melanin production is smaller, and the skin is fairer.

It can be seen from this process that "tyrosinase" plays a decisive role in melanin. Through various studies, it has been found that the stronger the activity of tyrosinase, the faster the formation of melanin, leading to darker skin color. Tyrosine is an essential amino acid for physiological activities, and it exists in the human body in large quantities and widely. Tyrosinase activity in darker skin was about three times higher than in lighter skin.

Some research suggests that glutathione can affect the melanin production process. It may inhibit the formation of melanin by reducing oxidative stress and inhibiting the activity of tyrosinase, thereby blocking the production of dopa oxidase.

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1. The main function of glutathione is to remove free radicals in the human body

As an important antioxidant in the body, it protects the sulfhydryl groups in molecules such as many proteins and enzymes.

2. Glutathione can also improve human immunity

Glutathione maintains health, anti-aging, and can also protect hemoglobin from hydrogen peroxide oxidation, free radicals and other oxidations, so that it can continue to normally carry out the ability to transport oxygen.

3. Glutathione can also inhibit the fatty liver caused by alcohol damage to the liver and assist the liver in detoxification.

Glutathione can combine with toxic compounds, heavy metal ions or carcinogens that enter the human body, and promote their excretion from the body to neutralize and detoxify.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.


Tag: Glutathione GSH

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