The role of nicotinamide adenine dinucleotide

 

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme widely present in living organisms and participates in many biochemical reactions. Together with ATP (adenylate), it serves as a key substance in energy metabolism. However, in recent years, scientists have discovered that NAD+ also plays an important role in the antioxidant process.

Through its special chemical structure, NAD+ can effectively scavenge free radicals in cells and reduce their damage to cell structures. The reaction process between NAD+ and free radicals can form more stable substances, thus avoiding further damage to cells.

NAD+ is involved in the intracellular respiration process. In this process, NAD+ reacts with oxygen to generate more stable NADH, which is an important energy carrier. This process will generate some free radicals, but NAD+ can effectively remove these free radicals through its own structural characteristics, thereby avoiding oxidative stress.

NAD+ is an activator of some important antioxidant enzymes, such as SIRT1 (deacetylase-like enzyme) and PARP (polyspermine polypolymerase). These enzymes protect cells from oxidative damage by counteracting the damage caused by the generation of free radicals and oxidative stress.

In addition, NAD+ also plays an important role in some special metabolic processes. For example, it participates in the beta-oxidation process of fatty acids. Some free radicals are also generated during this process, but the antioxidant effect of NAD+ ensures that these free radicals are eliminated in time.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.