PQQ naturally exists in a variety of foods such as milk, eggs, spinach, etc. In the United States, PQQ is managed as a "generally recognized as safe substance (GRAS)" and can be used as a raw material in energy drinks, sports drinks, electrolyte drinks and other foods; in the European Union and CaNADa, it is used as a dietary supplement or natural health food.
PQQ is a very potent antioxidant that plays an important role in brain cognition and memory. PQQ can inhibit the formation of peroxynitrite; it can potentially oxidize the redox site of N-methyl-D-aspartate (NMDA) receptor, thereby reducing the activity of NMDA receptor; it can be used as an effective Antioxidants to protect mitochondrial lipids and proteins and have been shown to protect mitochondrial function from oxidative damage; can promote the generation of new mitochondria and neurons. An 8-week trial in Japan showed that PQQ is effective on stress, fatigue, quality of life and sleep, and can improve mood .
At present, PQQ supplements are mainly aimed at brain health, sleep aid, ability supplement, etc., and are often used in combination with MNM, Coenzyme Q10, PS and other raw materials.
The application of PQQ in the health food market has received increasing attention. In 2020, a report published by market research organization QYResearch showed that the global PQQ market size is expected to reach US$320 million in 2026. With the improvement of people's health awareness, PQQ as a health product may become a new choice for people to pursue a healthy life.
Nakano, Masahiko & Yamamoto, Tetsuro & Okamura, Hisayoshi & Tsuda, Akira & Kowatari, Yasuyuki. (2012). Effects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and Sleep. Funct. Foods Health Dis. 2. 307-324. 10.31989/ffhd.v2i8.81.
*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.