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Enzymatic production is a bioengineering technology that utilizes biological catalysts—enzymes—to catalyze chemical reactions, thereby achieving product manufacturing.
High efficiency: Enzymes have a very high catalytic efficiency.
Specificity: Enzymes possess a high degree of specificity, with strict requirements for the structure of substrates.
Mildness: Enzyme-catalyzed reactions typically occur under relatively mild conditions, such as at ambient temperature, normal pressure, and near-neutral pH values. This represents a significant advantage compared to traditional chemical production methods.
Environmentally friendly: Due to the mild reaction conditions of enzymatic production, it generally does not produce large amounts of harmful waste. Compared to traditional chemical synthesis methods, it reduces environmental pollution. For example, in some organic synthesis processes, traditional chemical methods may result in significant emissions of volatile organic solvents and waste residue, while enzymatic production can avoid these issues.
High product quality: The specificity of enzymes ensures high purity of the products and enables the synthesis of complex-structured compounds. In fields such as pharmaceuticals and food, where product quality is highly demanded, enzymatic production offers significant advantages. For instance, in the enzymatic synthesis of certain drug intermediates, the accuracy and purity of the structure meet stringent pharmaceutical quality standards.
Food industry: Enzymatic production is widely used in food processing. For example, in the production of high-fructose syrup, glucose isomerases convert glucose to fructose, enhancing the sweetness of food. Fructose is sweeter than sucrose and has a relatively smaller impact on blood sugar levels. In cheese production, rennet can coagulate milk to form the curd structure of cheese.
Pharmaceutical industry: It is used for the production of drugs and drug intermediates. For example, in the production of antibiotics, some enzymes can be used to modify the structure of antibiotics to enhance their antibacterial activity or reduce toxicity. In insulin production, enzymatic methods can modify insulin to improve its stability and bioavailability.
Chemical industry: In the field of fine chemicals, enzymatic production can synthesize special chemicals. For example, in the synthesis of certain chiral compounds, enzymatic methods can utilize the stereoselectivity of enzymes to efficiently produce compounds with specific chiral structures, which are important in the pharmaceutical and fragrance industries.
Currently, the "Enzymatic synthesis coupled with ATP regeneration technology" platform established by Anhui GSH Bio-Technology Co., LTD. represents a significant breakthrough in the industrialization of synthetic biotechnology. By using AI to simulate directed mutations of natural enzymes and then employing genetic engineering techniques to screen for enzyme modules suitable for industrialization and capable of modular assembly, the company optimizes reaction processes and produces different products using various enzyme module combinations.
Using this platform technology, the company has achieved low-carbon production of products such as reduced glutathione, Nicotinamide Mononucleotide, cytidine diphosphate choline, creatine phosphate, and S-adenosylmethionine. It has also obtained certifications from various systems, including ISO9001, HACCP, FSSC22000, FDA, HALAL, KOSHER, and BRCGS. Thanks to the use of advanced synthetic biology techniques, the products have a high cost-performance ratio and are exported to more than 70 countries and regions worldwide, receiving high praise from customers.
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