What are the popular anti-aging raw materials?

by: GSHWORLD time: 2024-06-11 classify: Technological Innovation

With the rise of the anti-aging trend, the global anti-aging market size continues to grow, and consumers have higher and higher requirements for product quality. Ingredients and efficacy are the main factors for selection. In the field of anti-aging, NMN and PQQ are popular ingredients in recent years.

1. Nicotinamide Mononucleotide (NMN)

NMN is a precursor for NAD+ biosynthesis and has received widespread attention for its anti-aging properties. In biological models, the intake of NMN has been shown to improve age-related diseases and may delay death.

Anti-aging function of NMN:

1. Enhance NAD+ metabolism

2. Restore Sirt1 levels

3. Enhance DNA repair

4. Utilize mitochondrial excitatory effects

Application of NMN raw materials in various countries:

NMN can be used as a new cosmetic raw material in China, Japan allows NMN as a food raw material, and Canada is a natural health product. It must be approved by the Canadian Ministry of Health before it can be put on the market. It is currently being studied as a new drug in the United States.

Application of NMN raw materials in various countries

2. Pyrroloquinoline Quinone (PQQ) disodium salt

PQQ is an antioxidant found in various foods and human breast milk, and shows potential health benefits due to its growth-promoting, anti-obesity and neuroprotective functions. Studies have shown that PQQ can inhibit oxidative stress by improving mitochondrial function, thereby preventing inflammatory aging.

Anti-aging function of PQQ:

1. Promote mitochondrial function

2. Powerful antioxidant properties

3. Anti-inflammatory properties

Application of PQQ raw materials in various countries:

China: Approved as a new food raw material, recommended consumption is ≤20mg/day

United States: "Generally Recognized as Safe (GRAS)"

EU: Authorized as a new food, recommended consumption is ≤20mg/day

Canada: It is a natural health product and must be approved by Health Canada before listing.

References:

[1] Rahman SU, Qadeer A, Wu Z. Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging. Aging Dis. 2024 Apr 1;15(2):565-583. doi: 10.14336/AD.2023.0519-1. PMID: 37548938; PMCID: PMC10917541.

[2] Ishak N S M, Kikuchi M, Ikemoto K. Dietary pyrroloquinoline quinone hinders aging progression in male mice and D-galactose-induced cells[J]. 2024.

Tag: NMN , PQQ