With the continuous advancement of modernization, people's demand for skin health is increasing. Whitening is one of the goals pursued by many people. Oral ingestion of functional food ingredients has become a new way of skin whitening.
Functional food raw materials have attracted extensive attention because of their effects on regulating physiological functions. Its main ingredients include collagen, vitamin C, grape seed extract, glutathione, etc. These ingredients can promote skin metabolism, improve skin elasticity, reduce pigmentation, and achieve the effect of whitening skin. Reduced glutathione is consistent with the active glutathione in the human body, so it can be absorbed by the body more quickly and efficiently use.
Glutathione is a natural active peptide with important physiological functions, composed of glutamic acid, cysteine and glycine. Glutathione exists in two forms in the body, namely reduced glutathione (GSH for short) and oxidized glutathione (GSSG). Among them, reduced glutathione is the active form, and under physiological conditions The lower proportion is the most, about 95%, and has a high free radical scavenging rate. The glutathione usually referred to is reduced glutathione, which is an important endogenous antioxidant in the human body. Oxidized glutathione can assist reduced glutathione to scavenge free radicals.
In the structure of glutathione, there is an active sulfhydryl group attached to the side chain group of cysteine, which is the structural basis of many important physiological functions of glutathione, and can protect the sulfhydryl group of important enzyme proteins in the body from being oxidized and inactivated. Conducive to the play of enzyme activity. Combining sulfhydryl groups with free radicals in the body can directly reduce free radicals to easily metabolized acids, thereby reducing the damage of free radicals to the body.
As a powerful antioxidant, glutathione can remove excess free radicals, such as hydrogen peroxide, peroxide free radicals, etc., protect the sulfhydryl groups in proteins from oxidation, repair damaged sulfhydryl groups, and restore protein activity. , to make skin cells healthier.
2. Whitening and blemish
Glutathione can act on two key links in the formation mechanism of human skin melanin, breaking down blackness from the source layer by layer: by affecting the activity of skin cell tyrosinase, inhibiting melanin production; decomposing existing melanin, comprehensively combating melanin, thus preventing The occurrence of stains.
Glutathione can delay cell aging, accelerate cell regeneration, and improve skin aging. In 2017, a double-blind control group clinical trial 1 was conducted abroad. The intervention group was supplemented with 250 mg of reduced glutathione (GSH) group per day and the same dose of oxidized glutathione (GSSG) group. After 12 weeks of the test period , found that both GSH and GSSG can improve the skin condition of the intervention group. Compared with the control group, all subjects had reduced dark spots caused by ultraviolet rays, and some subjects had reduced skin wrinkles and increased skin elasticity after glutathione supplementation.