Glutathione is a short peptide composed of 3 amino acids that is found in almost every cell of the body and has two important antioxidant effects and integrated detoxification effects.
Glutathione can help maintain normal immune system function, and has antioxidant and integrated detoxification effects. It can not only be used in medicines, but also can be used as the base material of functional foods to delay aging, enhance immunity, and fight tumors. Sexual food is widely used.
At present, glutathione drugs have been developed artificially and are widely used in clinical practice. In addition to using its sulfhydryl group to chelate heavy metals, fluoride, mustard gas and other toxin poisoning, it is also used in hepatitis, hemolytic diseases, keratitis, and cataracts. and retinal diseases, etc., as an auxiliary treatment drug.
Glutathione functions and effects
Melanocytes are probably located in the basal layer of the epidermis of the human body. When the skin is exposed to ultraviolet rays, melanocytes secrete melanin.
Glutathione can interfere with the synthesis of melanin. Its main mechanisms include: glutathione can directly inhibit the activity of tyrosinase; interfere with the cell transfer of tyrosinase to forward melanosomes; the inhibition of tyrosinase is This is achieved indirectly through its antioxidant effect.
The aging process of organisms is the result of the accumulation of free radicals continuously produced by tissue cells of the body. Glutathione exists in reduced form (GSH) and oxidized form (GSSG).
Glutathione has powerful antioxidant capabilities and has been shown to scavenge the production of reactive oxygen species in epidermal cells induced by ultraviolet radiation.
Reactive oxygen species can act on proteins, such as directly hydrolyzing collagen peptide chains, or directly breaking the peptide chains from α-carbon atoms. Glutathione can scavenge free radicals and prevent protein from being oxidized.
Traditionally, GSH in the nucleus has been considered a protector of DNA and DNA-binding proteins from oxidative stress and radiation-induced damage, and studies have shown that exogenous addition of GSH can effectively reduce radiation-induced micronuclei and chromosomal aberrations in different systems. .