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Citicoline sodium may improve AAMI?

Author: GSHWORLD Release time: 2024-04-30 Column: Product News


Cognitive function refers to an individual's ability to process information, including memory, attention, language, and problem solving. As we age, cognitive function may gradually decline, leading to problems such as memory loss and slower reaction speeds. In recent years, Citicoline Sodium has been widely studied as a potential neuroprotective agent for its improvement in cognitive function.

Related experimental research

A Japanese research team investigated the effects of citicoline supplements on memory in healthy older adults with AAMI (age-related memory impairment). A total of 100 healthy men and women aged 50-85 years with AAMI participated in this randomized, double-blind, placebo-controlled trial.

After the 12-week intervention, subjects who took citicoline supplements showed significantly greater improvements in episodic memory than those who took a placebo. Four memory tests (spatial span, monkey ladder, paired associates, and digit span) also improved significantly with citicoline supplementation compared to placebo.

Studies have shown that citicoline supplements can improve memory performance, especially episodic memory, in people with AAMI, and that regular consumption of citicoline supplements may be safe and may help prevent memory loss due to aging. 


Application of Citicoline in Elderly and Neurodegenerative Populations

1. Elderly people

Cognitive function in older adults may gradually decline as they age. Citicoline sodium can improve the cognitive functions of the elderly, especially memory and attention, through the above-mentioned mechanisms.

2. Patients with neurodegenerative diseases

Citicoline has also shown potential benefit in patients with neurodegenerative diseases such as Alzheimer's disease. It can slow down the decline of cognitive function through mechanisms such as antioxidant and promoting neurotransmitter synthesis.

Safety and side effects

Safety and side effects

Citicoline is generally considered safe and tolerated by most people. However, some individuals may experience mild side effects, such as headache, insomnia, or gastrointestinal discomfort. Before using citicoline sodium supplements, it is recommended to consult a doctor, especially for people with specific health problems.

Citicoline, as a natural brain nutrient, has a positive effect on improving cognitive function through multiple mechanisms. It shows potential applications in the elderly population, patients with neurodegenerative diseases, and those who need to improve cognitive performance. However, more clinical studies and long-term follow-up studies are necessary to further verify the efficacy and safety of citicoline. Additionally, individual responses to citicoline may vary, so you should follow your doctor's advice and guidance when considering using citicoline supplements.


[1] Nakazaki E, Mah E, Sanoshy K, et al. Citicoline and memory function in healthy older adults: a randomized, double-blind, placebo-controlled clinical trial[J]. The Journal of nutrition, 2021, 151(8 ): 2153-2160.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

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