Glutathione applications in animal production

 

Research on glutathione (GSH) in animal production mainly focuses on improving the antioxidant performance, growth performance, anti-stress ability and breeding ability of animals. In recent years, it has been obtained in aquatic animals, pigs, chickens, sheep, cattle and other animals. Extensive research and applications.

1. Effect of GSH on antioxidant properties of animals

GSH can significantly improve the antioxidant properties of animals.

Studies have shown that adding GSH to the diet of 28-day-old weaned piglets can significantly increase the serum GSH-Px activity and IgG content of weaned piglets. In addition, GSH can significantly increase the GSH and IgG contents in the serum of broiler chickens; the activities of antioxidant enzymes such as SOD and CAT in the serum of fattening sheep in the experimental group supplemented with GSH in the feed are significantly higher than those in the control group.

In addition, the antioxidant properties of GSH have also been well verified in aquatic products, meat sheep and other animals.

2. Effect of GSH on animal growth

GSH can significantly improve the growth performance of animals.

Studies have shown that adding 20 mg/kg GSH to the diet of fattening pigs can significantly increase the daily weight gain, carcass lean meat rate and feed utilization rate of experimental pigs; in the study of weaned piglets, it was found that the serum IGF-1 of pigs in the experimental group The level was significantly higher than that of the control group, and the expression of IGF-1 mRNA in liver and muscle was also significantly higher than that of the control group.

In research on chickens, it was found that GSH can significantly improve the weight gain rate and feed utilization rate of yellow-feathered broilers; GSH can also significantly improve the proliferation ability, glucose absorption function and cell membrane enzyme activity of chicken small intestinal epithelial cells.

In studies on sheep, adding GSH to the diet significantly improved the weight gain rate and feed utilization rate of mutton sheep; GSH can also significantly increase the serum IGF-1 and GH levels of mutton sheep.

In addition, multiple studies have found that the production performance of aquatic animals in the GSH test group was significantly improved.

3. Effect of GSH on animal anti-stress

GSH can significantly improve the animal's anti-stress ability, improve the animal's resistance and survival rate in adverse environments.

In research on aquatic animals, it was found that GSH can effectively reduce the stress of microcystin on yellow catfish and grass carp, and improve the anti-stress ability.

In research on chickens, it was found that GSH can improve the resistance of chicks to coccidiosis and improve the survival rate of chicks; GSH can also inhibit the adverse effects of high concentrations of copper ions on the mitochondria of broiler liver cells and protect the mitochondrial respiratory chain complex of broilers. body.

4.The impact of GSH on animal breeding

GSH has a good effect on cell preservation in animal breeding.

In pig research, it was found that adding 1 mmol/L glutathione to the culture medium could reduce the generation of ROS during semen freezing and significantly improve the viability, vitality and acrosome integrity of frozen sperm after thawing.

In studies on cattle, it was found that adding 3.2mmol/L GSH to the culture medium could significantly improve the viability, longevity and fertilization rate of bovine sperm after cryopreservation and thawing.

In addition, during in vitro embryo development, adding GSH to the culture medium can improve the development success rate and survival rate of embryos at each stage.

In short, the unique molecular structure of GSH enables it to possess multiple physiological functions such as antioxidant, anti-stress, and detoxification, so it plays a very important role in the healthy growth of animals. With the continuous deepening of research, the relevant mechanisms and principles of GSH's effects on animals will become clearer, and its application prospects will also be broader.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.