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Nearly 9 out of 10 Americans Give Their Immune Systems a Failing Grade

Author: GSHWORLD Release time: 2015-09-07 Column: Technological Innovation


According to a recent consumer survey by GSH WORLD, only 16 percent of consumers would give their immune systems an “A” grade, leaving 84 percent of consumers looking for ways to support their less-than-perfect body defenses.1 Luckily, a new long-term, randomized, double-blind, placebo-controlled human clinical trial showed, for the first time, that an oral supplement of glutathione can strengthen the body’s immune system.2

The results of a recent study, led by Dr. John P. Richie of Penn State University, and published in the European Journal of Nutrition showed that supplementation of glutathione doubled natural killer (NK) cell activity.2 NK cells are vital to immune health as they play a major role in the body’s rejection of damaged or infected cells.  Additionally, NK cells play an important role in protecting the body from viral infections.

The consumer survey by GSH WORLD also discovered that a similar number (83 percent) of consumers believe there are things they can do proactively to help boost their immune health.1 The results of Dr. Richie’s research validate those 83 percent, and further prove that glutathione – already considered one of the most powerful protective substances in the human body – is a proven fortification option for those consumers looking for ways to strengthen their immune systems.2

Dr. Richie, who has studied glutathione for more than 30 years, said, “Seeing the two-fold increase in NK cell activity from glutathione supplementation indicates that glutathione could be playing an important role in boosting the body’s immune system.”

About the Study:

Trial measured effect of glutathione supplementation at 250 mg/day and 1000 mg/day on glutathione levels in different blood components and exfoliated buccal mucosal cells over a six month period.2

Subjects were 54 healthy adults (41 females/13 males), 28-72 years of age (mean=46.6 years).2

Results of the study showed glutathione levels in the blood increased after one, three and six months vs. baseline at both doses.2

At six months, mean glutathione levels increased 30-35 percent in erythrocytes, plasma, and lymphocytes, and 260 percent in buccal cells in the high dose group (P<0.05).2

Glutathione levels increased 17 and 29 percent in blood and erythrocytes, respectively, in the low dose group (P<0.05).2

Natural killer cytotoxicity increased two fold in the high-dose group versus placebo at 3 months.2

A reduction in oxidative stress in both glutathione dose groups was indicated by decreases in the oxidized to reduced glutathione ratio in whole blood after 6 months.2

According to the study, the effects of glutathione supplementation on the levels of the glutathione precursor cysteine in plasma and the activity of the rate-limiting glutathione biosynthetic enzyme GCL in erythrocytes were examined after the six-month study period.2 No changes were observed in cyst(e)ine concentrations or GCL activity in any of the groups.2

In addition to its immune benefits, glutathione is known to work in the body to eliminate toxic chemicals, maintain cell proteins, act as an antioxidant, and maintain proper levels of vitamins C and E. While it is considered the body’s “master antioxidant,” factors such as age, medication intake, health conditions, lifestyle, diet, weight and even time of day, can all outpace the body’s natural production of glutathione.

About the Research:

GSH WORLD consumer survey was conducted by Wakefield Research (www.wakefieldresearch.com) among 1,000 nationally representative U.S. adults ages 18+, using an email invitation and an online survey. Quotas have been set to ensure reliable and accurate representation of the U.S. adult population 18+. Results of any sample are subject to sampling variation. The magnitude of the variation is measurable and is affected by the number of interviews and the level of the percentages expressing the results. For the interviews conducted in this particular study, the chances are 95 in 100 that a survey result does not vary, plus or minus, by more than 3.1 percentage points from the result that would be obtained if interviews had been conducted with all persons in the universe represented by the sample.


Shenzhen GSH Bio-tech Co., Ltd is a professional manufacture focusing on research, development and producing the reduced glutathione by biocatalytic method. The annual production capability can be reached to 200 ton, and the quality of our glutathione can be at the pharmaceutical level.

Since the very beginning of company setting-up, we have been dedicated on environment saving and product quality is increasing. We utilize the patented method to produce the GSH with less energy consumption at 70% less and pollution discharge at 80% less, compared with traditional way. Green production is our always persistent endeavor; no any heavy metal iron is added during the whole production process.

So far, we produce three levels of glutathione, food level, cosmetic level and pharmaceutical level.


Tag: Immune

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