News

Lipoic acid (α-lipoic acid, ALA), a naturally occurring bioactive molecule, serves not only as an essential cofactor in mitochondrial energy metabolism but also demonstrates remarkable efficacy in antioxidant, anti-inflammatory, and neuroprotective functions.

After nearly three years of relentless pressure from the Natural Products Association (NPA), the Food and Drug Administration has reversed its position and formally recognized β-nicotinamide mononucleotide (NMN) as a lawful dietary-supplement ingredient.

GSH detoxifies H₂O₂, lipid peroxides, methylglyoxal and pesticides. It protects proteins via glutathionylation and drives the ascorbate–glutathione (AsA-GSH) cycle that regenerates ascorbate from dehydroascorbate.

By being converted to GSH, γ-glutamylcysteine helps scavenge oxygen free radicals, detoxify reactive oxygen species, modulate enzyme activity, take part in metabolism, and strengthen immunity.

Future work should focus on optimizing NR formulation and enhancing its metabolic stability to unlock its full clinical potential.

Although food supplements can mitigate oxidative stress through multiple mechanisms, they differ markedly in efficacy and suitable scenarios because of variations in chemical composition, molecular targets and biochemical pathways.

As research progresses, citicoline could assume a larger role in preventing cognitive decline and bolstering mental performance, giving the public a new, evidence-backed option for brain maintenance.

Achieving visible reduction in hyperpigmentation is a long-term commitment.

Yet two understated all-rounders—glutathione (GSH) and carnosine—rarely grab the headlines, even though they quietly solve some of skin’s biggest headaches.

Accumulating evidence suggests PQQ may eventually be recognized as an essential vitamin-like factor for humans.

Next stop: SupplySide West in Las Vegas this October.

Adenosine—an endogenous nucleoside—has emerged as a promising topical active ingredient.

Glutathione (GSH), a key non-enzymatic antioxidant in plants, not only maintains cellular redox homeostasis but also, when applied exogenously, effectively boosts seed vigour, offering a practical solution to poor germination under adverse conditions.

Citicoline is a key neuroprotective molecule that markedly counters neuronal damage. When neurons face oxidative stress, it exerts powerful protective effects.

As public interest in health grows, dietary supplements are attracting more attention for improving general and cutaneous well-being.

Phosphocreatine (CP) is one of the key substances involved in cellular energy metabolism in the human body.

The naturally occurring compound S-adenosylmethionine (SAMe) is emerging as a promising hepatoprotective agent, with a recent systematic review providing robust evidence for its use.